The 3D Tissue Analytics System
See beyond the section with high-resolution 3D imaging of FFPE tissue – without staining or slicing.
Why 3D?
Explore virtual sections in any orientation without consuming your sample. Follow structures through the volume, measure their spatial relationships, and identify regions for targeted histology. Your tissue remains available for subsequent staining and molecular analysis.
Applications
Explore spatial questions in FFPE tissue. We help assess which imaging approach and analyses fit your samples and study.
How much tumor tissue is present, and where is it located? Explore its spatial distribution and discuss sample-specific approaches to 3D quantification.
How are vessels organized in space? Follow branching networks and explore their relationship to surrounding tissue.
Where are lesions within the tissue, and how are they distributed? Explore their spatial context and identify regions for closer investigation.
How does a tumor extend through the tissue? Inspect its relationship to surrounding structures, vessels, and the specimen boundary.
Where should you look more closely? Locate regions of interest in 3D to guide subsequent histology, IHC, and further tissue analysis.
3D tissue data delivers quantitative, reproducible endpoints for pre-clinical drug testing – providing objective, explainable readouts of pathological progression and treatment effects in small-animal models.
Histomography’s X-ray imaging offers exceptional capabilities for analyzing complex tissue samples in both basic research and translational biomedicine.
Whole-organ 3D datasets from FFPE lungs allow localization and quantification of fibrotic lesions, guiding targeted histology and robust model classification.
Truly impressive. Getting started with and handling 3D data is very intuitive.
In the case of basal cell carcinomas, precise margin assessment is critical. With 3D data, this is achieved on an entirely new level.
2D sections are insufficient to fully capture tissue architecture. 3D phase-contrast imaging provides the missing information.
Workflow
We make it easy to turn your samples into 3D data
Send us your FFPE samples or scan them in your own lab with our one-click scanning workflow - no staining or slicing required.
Access your scans in the browser. Explore the volume, inspect virtual sections, and share findings with your team.
Turn spatial data into measurements and application-specific readouts. Co-develop AI-supported analyses around your samples and questions.
Built for your laboratory
3D X-ray tissue microscopes. One-Click. Fully Automated.
The big picture, in 3D.
High resolution, right where it matters.
Scout & slice: overview the block on the Block Scanner → punch the region of interest → analyse it at 2 µm on the Punch Scanner.
Scans as a Service
Receive publication-ready 3D data with the same quality as our lab systems. Your samples are returned to you after scanning, ready for conventional histology, IHC, and molecular analysis. Choose the resolution that fits your question:
In-lab
10 µm
Whole Block
Whole-block overview, non-destructive.
In-lab
2 µm
5 mm core punch
ROI-focused, fine structure.
Synchrotron
0.65 µm
1.5 mm core punch
Highest resolution without a beamtime application.
Results delivered in Histomography Cloud · download as raw, tiff, numpy, or rek · plus optional application-specific & AI-supported 3D analyses.
Histomography Cloud
Every scan lands in Histomography Cloud, running on Stacks — our 3D streaming technology. View, measure, annotate, and share. No installation, any operating system, even mobile.
Request a demo, discuss a scan service, or find the right system for your lab. Talk to our team about your research and the next step.